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1

Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors

Yongmun Choi, Farisa Syeda, John R. Walker, Patrick J. Finerty Jr., Dominic Cuerrier, Amy Wojciechowski, Qingsong Liu, Sirano Dhe-Paganon, Nathanael S. Gray

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 307 KB

english, 2009

2

Un outil pour le recueil des expositions professionnelles et l’évaluation des risques lors de la visite médicale

Binet, P., Dhe, L., Le Meur, B., Monticelli-Vigneron, G.

Journal:

Archives des Maladies Professionnelles et de l'Environnement

Year:

2004

Language:

french

File:

PDF, 21 KB

french, 2004

3

Crystal Structure of the Pleckstrin Homology-Phosphotyrosine Binding (PH-PTB) Targeting Region of Insulin Receptor Substrate 1

Sirano Dhe-Paganon, Elizabeth A. Ottinger, Robert T. Nolte, Michael J. Eck and Steven E. Shoelson

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.36 MB

english, 1999

4

The Replication Focus Targeting Sequence (RFTS) Domain Is a DNA-competitive Inhibitor of Dnmt1

Syeda, F., Fagan, R. L., Wean, M., Avvakumov, G. V., Walker, J. R., Xue, S., Dhe-Paganon, S., Brenner, C.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.74 MB

english, 2011

5

Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins

Korzhnev, Dmitry M., Neculai, Dante, Dhe-Paganon, Sirano, Arrowsmith, Cheryl H., Bezsonova, Irina

Journal:

Journal of Biomolecular NMR

Year:

2016

Language:

english

File:

PDF, 4.05 MB

english, 2016

6

Impact of nicotine replacement therapy as an adjunct to anti-tuberculosis treatment and behaviour change counselling in newly diagnosed pulmonary tuberculosis patients: an open-label, randomised controlled trial

Sharma, Surendra Kumar, Mohan, Alladi, Singh, Achintya Dinesh, Mishra, Hridesh, Jhanjee, Sonali, Pandey, Ravindra Mohan, Singh, Binit Kumar, Sharma, Rohini, Pallipamu, Prakash Babu, Pai, Madhukar, Dhe

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

7

Studies on the Coma cluster. III. The virial mass and kinematics

Jun-liang Zhao, Song-nian Huang, Rong-shi Pan, Yan-ping dHe

Journal:

Chinese Astronomy and Astrophysics

Year:

1991

Language:

english

File:

PDF, 622 KB

english, 1991

8

Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A

Alexander Lemak, Adelinda Yee, Irina Bezsonova, Sirano Dhe-Paganon, Cheryl H. Arrowsmith

Journal:

Journal of Biomolecular NMR

Year:

2011

Language:

english

File:

PDF, 1.81 MB

english, 2011

9

The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1)

Tara L. Davis, John R. Walker, Hui Ouyang, Farrell MacKenzie, Christine Butler-Cole, Elena M. Newman, Elan Z. Eisenmesser, Sirano Dhe-Paganon

Journal:

Year:

2008

Language:

english

File:

PDF, 1009 KB

english, 2008

10

Distinguishing between calpain heterodimerization and homodimerization

Ravikiran Ravulapalli, Robert L. Campbell, Sherry Y. Gauthier, Sirano Dhe-Paganon, Peter L. Davies

Journal:

Year:

2009

Language:

english

File:

PDF, 412 KB

english, 2009

11

Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases

Tara L. Davis, John R. Walker, Abdellah Allali-Hassani, Sirlester A. Parker, Benjamin E. Turk, Sirano Dhe-Paganon

Journal:

Year:

2009

Language:

english

File:

PDF, 885 KB

english, 2009

12

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

Avvakumov, George V., Walker, John R., Xue, Sheng, Li, Yanjun, Duan, Shili, Bronner, Christian, Arrowsmith, Cheryl H., Dhe-Paganon, Sirano

Journal:

Year:

2008

Language:

english

File:

PDF, 708 KB

english, 2008

13

A phenylalanine zipper mediates APS dimerization

Dhe-Paganon, Sirano, Werner, Eric D, Nishi, Masahiro, Hansen, Lone, Chi, Young-In, Shoelson, Steven E

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 648 KB

english, 2004

14

Fold of the conserved DTC domain in deltex proteins

Josiah Obiero, John R. Walker, Sirano Dhe-Paganon

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

15

Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3)

Tara L. Davis, John R. Walker, Peter Loppnau, Christine Butler-Cole, Abdellah Allali-Hassani, Sirano Dhe-Paganon

Journal:

Year:

2008

Language:

english

File:

PDF, 2.66 MB

english, 2008

16

Structure of human protein kinase C eta (PKCη) C2 domain and identification of phosphorylation sites

Dene R. Littler, John R. Walker, Yi-Min She, Patrick J. Finerty Jr., Elena M. Newman, Sirano Dhe-Paganon

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 1.92 MB

english, 2006

17

539 Crystallisation and characterisation of the phosphorylation domain of the ryanodine receptor

P. Sharma, W. Li, U. Nair, T. Miyake, A. Dong, T. Kislinger, S. Dhe-Paganon, A.O. Gramolini

Journal:

Canadian Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

18

The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition

Tara L. Davis, John R. Walker, Patrick J. Finerty Jr, Farrell Mackenzie, Elena M. Newman, Sirano Dhe-Paganon

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 2.25 MB

english, 2007

19

Structural insights into the inhibited states of the Mer receptor tyrosine kinase

Xudong Huang, Patrick Finerty Jr., John R. Walker, Christine Butler-Cole, Masoud Vedadi, Matthieu Schapira, Sirlester A. Parker, Benjamin E. Turk, Debra A. Thompson, Sirano Dhe-Paganon

Journal:

Journal of Structural Biology

Year:

2009

Language:

english

File:

PDF, 1.60 MB

english, 2009

20

A centrifugation-free high-throughput protein purification system using in-line microfluidization

Denis Alenkin, Laila Yermekbayeva, Shariq Mujib, Anders Vesterberg, Elena Newman, Ken Yamazaki, Doug Cossar, Sirano Dhe-Paganon

Journal:

Protein Expression and Purification

Year:

2011

Language:

english

File:

PDF, 669 KB

english, 2011

21

Crystal Structure of the Tyrosine Phosphatase SHP-2

Peter Hof, Scott Pluskey, Sirano Dhe-Paganon, Michael J Eck, Steven E Shoelson

Journal:

Year:

1998

Language:

english

File:

PDF, 5.41 MB

english, 1998

22

Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor

Michael J. Eck, Sirano Dhe-Paganon, Thomas Trüb, Robert T. Nolte, Steven E. Shoelson

Journal:

Year:

1996

Language:

english

File:

PDF, 2.00 MB

english, 1996

23

Diabetes Mutations Delineate an Atypical POU Domain in HNF-1α

Young-In Chi, J.Daniel Frantz, Byung-Chul Oh, Lone Hansen, Sirano Dhe-Paganon, Steven E. Shoelson

Journal:

Year:

2002

Language:

english

File:

PDF, 654 KB

english, 2002

24

Structural determination of the phosphorylation domain of the ryanodine receptor

Parveen Sharma, Noboru Ishiyama, Usha Nair, Wenping Li, Aiping Dong, Tetsuaki Miyake, Aaron Wilson, Tim Ryan, David H. MacLennan, Thomas Kislinger, Mitsuhiko Ikura, Sirano Dhe-Paganon, Anthony O. Gram

Journal:

Year:

2012

Language:

english

File:

PDF, 662 KB

english, 2012

25

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

Sheng, Y., Hong, J. H., Doherty, R., Srikumar, T., Shloush, J., Avvakumov, G. V., Walker, J. R., Xue, S., Neculai, D., Wan, J. W., Kim, S. K., Arrowsmith, C. H., Raught, B., Dhe-Paganon, S.

Journal:

Molecular & Cellular Proteomics

Year:

2012

Language:

english

File:

PDF, 2.46 MB

english, 2012

26

Crystal Structure of the HNF4alpha Ligand Binding Domain in Complex with Endogenous Fatty Acid Ligand

Dhe-Paganon, S.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 294 KB

english, 2002

27

Structure-reactivity correlations for reactions of substituted phenolate anions with acetate and formate esters

Stefanidis, Dimitrios, Cho, Sayeon, Dhe-Paganon, Sirano, Jencks, William P.

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 886 KB

english, 1993

28

FKBP Family Proteins: Immunophilins with Versatile Biological Functions

Kang, Cong Bao, Hong, Ye, Dhe-Paganon, Sirano, Yoon, Ho Sup

Journal:

Year:

2008

Language:

english

File:

PDF, 340 KB

english, 2008

29

Mass Spectrometry Following Mild Enzymatic Digestion Reveals Phosphorylation of Recombinant Proteins in Escherichia coli Through Mechanisms Involving Direct Nucleotide Binding

She, Yi-Min, Xu, Xiaohui, Yakunin, Alexander F., Dhe-Paganon, Sirano, Donald, Lynda J., Standing, Kenneth G., Lee, Daniel C., Jia, Zongchao, Cyr, Terry D.

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 3.09 MB

english, 2010

30

WITHDRAWN: Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1

Achour, Mayada, Mousli, Marc, Alhosin, Mahmoud, Ibrahim, Abdulkhaleg, Peluso, Jean, Muller, Christian D., Schini-Kerth, Valérie B., Hamiche, Ali, Dhe-Paganon, Sirano, Christian Bronner,

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 27 KB

english, 2012

31

Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1

Achour, Mayada, Mousli, Marc, Alhosin, Mahmoud, Ibrahim, Abdulkhaleg, Peluso, Jean, Muller, Christian D., Schini-Kerth, Valérie B., Hamiche, Ali, Dhe-Paganon, Sirano, Bronner, Christian

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 425 KB

english, 2013

32

Basic Tilted Helix Bundle – A new protein fold in human FKBP25/FKBP3 and HectD1

Helander, Sara, Montecchio, Meri, Lemak, Alexander, Farès, Christophe, Almlöf, Jonas, Li, Yanjun, Yee, Adelinda, Arrowsmith, Cheryl H., Dhe-Paganon, Sirano, Sunnerhagen, Maria

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

33

Two ZnF-UBP Domains in Isopeptidase T (USP5)

Avvakumov, George V., Walker, John R., Xue, Sheng, Allali-Hassani, Abdellah, Asinas, Abdalin, Nair, Usha B., Fang, Xianyang, Zuo, Xiaobing, Wang, Yun-Xing, Wilkinson, Keith D., Dhe-Paganon, Sirano

Journal:

Year:

2012

Language:

english

File:

PDF, 4.56 MB

english, 2012

34

Ring1B Contains a Ubiquitin-Like Docking Module for Interaction with Cbx Proteins ,

Bezsonova, Irina, Walker, John R., Bacik, John P., Duan, Shili, Dhe-Paganon, Sirano, Arrowsmith, Cheryl H.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.93 MB

english, 2009

35

Structure of Human Pancreatic Lipase-Related Protein 2 with the Lid in an Open Conformation †,‡

Eydoux, Cécilia, Spinelli, Silvia, Davis, Tara L., Walker, John R., Seitova, Alma, Dhe-Paganon, Sirano, De Caro, Alain, Cambillau, Christian, Carrière, Frédéric

Journal:

Year:

2008

Language:

english

File:

PDF, 6.56 MB

english, 2008

36

Mechanism of Mevalonate Pyrophosphate Decarboxylase: Evidence for a Carbocationic Transition State

Dhe-Paganon, Sirano, Magrath, Joe, Abeles, Robert H.

Journal:

Year:

1994

Language:

english

File:

PDF, 965 KB

english, 1994

37

Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity

Lukkarila, Julie L., da Silva, Sara R., Ali, Mohsin, Shahani, Vijay M., Xu, G. Wei, Berman, Judd, Roughton, Andrew, Dhe-Paganon, Sirano, Schimmer, Aaron D., Gunning, Patrick T.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 4.88 MB

english, 2011

38

Role of specific acidic lipids on the reconstitution of sodium-dependent amino acid transport in proteoliposomes derived from Ehrlich cell plasma membranes

Lin, Guorong, McCormick, John I., Dhe-Paganon, Sirano, Silvius, John R., Johnstone, Rose M.

Journal:

Year:

1990

Language:

english

File:

PDF, 884 KB

english, 1990

39

Immunogenicity of Recombinant Adenovirus-Human Immunodeficiency Virus Vaccines in Chimpanzees Following Intranasal Administration

LUBECK, MICHAEL D., NATUK, ROBERT J., CHENGALVALA, MURTY, CHANDA, PRANAB K., MURTHY, KRISHNA K., MURTHY, SHRIDHARA, MIZUTANI, SATOSHI, LEE, SHAW-GUANG, WADE, MARK S., BHAT, BHEEM M., BHAT, RAMESH, DHE

Journal:

AIDS Research and Human Retroviruses

Year:

1994

Language:

english

File:

PDF, 1.04 MB

english, 1994

40

Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini

Ouyang, H., Ali, Y. O., Ravichandran, M., Dong, A., Qiu, W., MacKenzie, F., Dhe-Paganon, S., Arrowsmith, C. H., Zhai, R. G.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 3.17 MB

english, 2012

41

Development of Fluorescent Substrates and Assays for the Key Autophagy-Related Cysteine Protease Enzyme, ATG4B

Nguyen, Thanh G., Honson, Nicolette S., Arns, Steven, Davis, Tara L., Dhe-Paganon, Sirano, Kovacic, Suzana, Kumar, Nag S., Pfeifer, Tom A., Young, Robert N.

Journal:

Assay and Drug Development Technologies

Year:

2014

Language:

english

File:

PDF, 703 KB

english, 2014

42

Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement

Yi, Joanna S., Federation, Alexander J., Qi, Jun, Dhe-Paganon, Sirano, Hadler, Michael, Xu, Xiang, St. Pierre, Roodolph, Varca, Anthony C., Wu, Lei, Marineau, Jason J., Smith, William B., Souza, Amand

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.86 MB

english, 2015

43

Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME

Bacik, J.-P., Walker, J. R., Ali, M., Schimmer, A. D., Dhe-Paganon, S.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 2.63 MB

english, 2010

44

Structural and Functional Comparison of the RING Domains of Two p53 E3 Ligases, Mdm2 and Pirh2

Shloush, J., Vlassov, J. E., Engson, I., Duan, S., Saridakis, V., Dhe-paganon, S., Raught, B., Sheng, Y., Arrowsmith, C. H.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 3.08 MB

english, 2011

45

Structure of the Globular Tail of Nuclear Lamin

Dhe-Paganon, S., Werner, E. D., Chi, Y.-I., Shoelson, S. E.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

46

Molecular Insights into the Function of RING Finger (RNF)-containing Proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent Ubiquitylation

Campbell, S. J., Edwards, R. A., Leung, C. C. Y., Neculai, D., Hodge, C. D., Dhe-Paganon, S., Glover, J. N. M.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.98 MB

english, 2012

47

Crystal Structure of Human Frataxin

Dhe-Paganon, S., Shigeta, R., Chi, Y.-I., Ristow, M., Shoelson, S. E.

Journal:

Journal of Biological Chemistry

Year:

2000

Language:

english

File:

PDF, 1.27 MB

english, 2000

48

Structural Basis of E2-25K/UBB+1 Interaction Leading to Proteasome Inhibition and Neurotoxicity

Ko, S., Kang, G. B., Song, S. M., Lee, J.-G., Shin, D. Y., Yun, J.-H., Sheng, Y., Cheong, C., Jeon, Y. H., Jung, Y.-K., Arrowsmith, C. H., Avvakumov, G. V., Dhe-Paganon, S., Yoo, Y. J., Eom, S. H., Le

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 3.02 MB

english, 2010

49

Kinase Activation through Dimerization by Human SH2-B

Nishi, M., Werner, E. D., Oh, B.-C., Frantz, J. D., Dhe-Paganon, S., Hansen, L., Lee, J., Shoelson, S. E.

Journal:

Molecular and Cellular Biology

Year:

2005

Language:

english

File:

PDF, 1.01 MB

english, 2005

50

Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III

Bezerra, G. A., Dobrovetsky, E., Viertlmayr, R., Dong, A., Binter, A., Abramic, M., Macheroux, P., Dhe-Paganon, S., Gruber, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012